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Year : 2022  |  Volume : 11  |  Issue : 3  |  Page : 182-184

Cellular leiomyoma versus endometrial stromal sarcoma: A report of a rare case presenting a diagnostic challenge on intraoperative frozen section

1 Department of Pathology, ESIC Medical College and Hospital, Faridabad, Haryana, India
2 Department of Obstetrics and Gynaecology, ESIC Medical College and Hospital, Faridabad, Haryana, India

Correspondence Address:
Dr. Varsha Chauhan
Department of Pathology, ESIC Medical College and Hospital, Faridabad - 121 001, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/GMIT.GMIT_53_20

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Endometrial stromal sarcomas (ESSs) account for approximately 0.2% of all uterine malignancies. Cellular leiomyoma (CL) often simulates low-grade ESS due to similar cytology. We report the case of a 34-year-old female with a mass per abdomen. Frozen sections showed a tumor with many thin- and thick-walled vessels along with hyaline material. A differential diagnosis of CL and endometrial stromal tumor was suggested. The index case was diagnostically challenging to pathologists. Paraffin sections supplemented by immunohistochemistry (smooth muscle actin, CD10, and beta-catenin) favored CL. Frozen section sometimes leads to over/underestimation of tumor in view of small sampling area of tumor.

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