CASE REPORT |
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Year : 2022 | Volume
: 11
| Issue : 3 | Page : 182-184 |
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Cellular leiomyoma versus endometrial stromal sarcoma: A report of a rare case presenting a diagnostic challenge on intraoperative frozen section
Charu Agarwal1, Mukta Pujani1, Varsha Chauhan1, Raina Chawla2, Anu Agarwal1, Reetika Menia1
1 Department of Pathology, ESIC Medical College and Hospital, Faridabad, Haryana, India 2 Department of Obstetrics and Gynaecology, ESIC Medical College and Hospital, Faridabad, Haryana, India
Correspondence Address:
Dr. Varsha Chauhan Department of Pathology, ESIC Medical College and Hospital, Faridabad - 121 001, Haryana India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/GMIT.GMIT_53_20
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Endometrial stromal sarcomas (ESSs) account for approximately 0.2% of all uterine malignancies. Cellular leiomyoma (CL) often simulates low-grade ESS due to similar cytology. We report the case of a 34-year-old female with a mass per abdomen. Frozen sections showed a tumor with many thin- and thick-walled vessels along with hyaline material. A differential diagnosis of CL and endometrial stromal tumor was suggested. The index case was diagnostically challenging to pathologists. Paraffin sections supplemented by immunohistochemistry (smooth muscle actin, CD10, and beta-catenin) favored CL. Frozen section sometimes leads to over/underestimation of tumor in view of small sampling area of tumor.
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